Detailed Characterizations
Characterization of Iron Colloidal Complex, NDDS, and Complex Molecule (SEC-GPC) at VitelyBio
Characterization of Iron Colloidal Complexes involves analyzing the physicochemical properties of iron-based nanoparticles used in various medical treatments, such as iron deficiency anemia. These complexes typically consist of an iron core surrounded by a carbohydrate shell, which stabilizes the particles and controls iron release in the body.
Nanoparticle Drug Delivery Systems (NDDS) are advanced formulations designed to deliver drugs more effectively to targeted areas in the body. Characterizing these systems ensures their stability, efficacy, and safety.
Size Exclusion Chromatography – Gel Permeation Chromatography (SEC-GPC) is a powerful analytical technique used to determine the molecular weight distribution and size of complex molecules. This method is crucial for ensuring the consistency and quality of pharmaceutical products.
How is it Done?
At VitelyBio, we employ state-of-the-art techniques and equipment to perform these characterizations:
Iron Colloidal Complexes
We use advanced physicochemical characterization methods to analyze the size, stability, and iron release profiles of iron colloids. This includes techniques like dynamic light scattering (DLS), transmission electron microscopy (TEM), and inductively coupled plasma mass spectrometry (ICP-MS).
NDDS
Our team conducts comprehensive studies to evaluate the encapsulation efficiency, release kinetics, and targeting capabilities of nanoparticle drug delivery systems. Techniques such as high-performance liquid chromatography (HPLC) and differential scanning calorimetry (DSC) are employed.
SEC-GPC
This technique involves passing the sample through a column packed with porous beads. Molecules are separated based on their size, allowing us to determine the molecular weight distribution and purity of complex molecules.